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Figure 3. The histone chaperone HIRA assembles the histone H3.3 into the HBV cccDNA. (A)

Journal: Annals of hepatology

Article Title: The histone variant H3.3 regulates the transcription of the hepatitis B virus.

doi: 10.1016/j.aohep.2020.09.005

Figure Lengend Snippet: Figure 3. The histone chaperone HIRA assembles the histone H3.3 into the HBV cccDNA. (A)

Article Snippet: For siRNA treatment, 10 nM of either control siRNA (Silencer negative control #1 siRNA, Ambion, Life Technologies) or human HIRA siRNA (sc-43836, Santa Cruz Biotechnology) were transfected with Lipofectamine 2000 48 h before HBV transfection. siRNA products from Santa Cruz Jo ur na l P re -p ro of Biotechnology consist of three to five 19-25 nt siRNAs target-specific designed to knockdown gene expression.

Techniques: